Changes of plasma B-type natriuretic peptide level during non-invasive ventilation in treating acute left heart failure.
- Author:
Hai-Yan ZHANG
1
;
Chun-Sheng LI
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Aged, 80 and over; Enzyme-Linked Immunosorbent Assay; Female; Heart Failure; blood; therapy; Humans; Intermittent Positive-Pressure Ventilation; methods; Male; Middle Aged; Natriuretic Peptide, Brain; blood; Treatment Outcome
- From: Acta Academiae Medicinae Sinicae 2008;30(2):140-143
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo assess the changes of B-type natriuretic peptide (BNP) levels during noninvasive ventilation in treating acute left heart failure.
METHODSTotally 28 patients with acute left heart failure were randomly assigned to group A (n = 13; without non-invasive ventilation) and group B (n = 15; undergoing non-invasive ventilation). Another 10 healthy adults were enrolled as the normal control group. Plasma BNP were obtained with ELISA before treatment and 3 and 7 hours after treatment.
RESULTSThe plasma BNP levels were significantly higher in group A and group B than in the normal control group before treatment (P< 0.01). Three and 7 hours after treatment, the plasma BNP levels was significantly higher in group A than in the normal control group (P<0.05), while it was significantly lower in group B than in group A (P<0.05, P<0.01).
CONCLUSIONThe plasma BNP level remarkably decreases in patients undergo non-invasive ventilation, suggesting that the plasma BNP level decreases along with the improvement of cardiac function.
