Metabonomics in medical and pharmaceutical research.
- Author:
Chang-Xiao LIU
1
Author Information
1. Tianjin National Key Laboratory of Pharmacokinetics and Pharmacodynamics, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China.
- Publication Type:Editorial
- MeSH:
Animals;
Biomarkers, Pharmacological;
metabolism;
Biomedical Research;
Diagnosis;
Drug Evaluation, Preclinical;
Humans;
Medicine, Chinese Traditional;
Metabolome;
Metabolomics;
Models, Animal;
Toxicity Tests
- From:
Acta Academiae Medicinae Sinicae
2007;29(6):712-718
- CountryChina
- Language:Chinese
-
Abstract:
Metabonomics is a new "-omics" science in post-gene time. Metabonomics can directly understand the physiological and biochemical situation by its "metabolome profile" as a whole, and therefore can provide various information that differs from other "-omics". Metabonomics has been applied in disease diagnosis, assessment of animal models, screening of new drugs, evaluation of drug safety, discovery of new bio-markers of toxicity, as well as research of traditional Chinese medicine.