Surgial treatment and prognosis of ovarian metastasis from colorectal cancer.
- Author:
Xu CHE
1
;
Yi SHAN
;
Zhi-Xiang ZHOU
;
Dong-Bing ZHAO
;
Jian-Jun BI
;
Yong-Fu SHAO
;
Ping ZHAO
Author Information
- Publication Type:Journal Article
- MeSH: Adenocarcinoma; secondary; surgery; Adenocarcinoma, Mucinous; secondary; surgery; Adult; Aged; Carcinoma, Signet Ring Cell; secondary; surgery; Colorectal Neoplasms; pathology; Female; Follow-Up Studies; Humans; Hysteroscopy; methods; Middle Aged; Ovarian Neoplasms; secondary; surgery; Ovariectomy; methods; Proportional Hazards Models; Retrospective Studies; Survival Rate
- From: Chinese Journal of Oncology 2007;29(11):864-866
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo summarize the surgical treatment experiece and to investigate the prognosis of the patients with ovarian metastasis from colorectal cancer.
METHODSThe data of 67 patients with synchronous or asynchronous ovarian metastasis from colorectal cancer surgically treated between January 1989 and December 2005 were collected and analyzed retrospectively using Statistical Package for the Social Sciences (Release 11.5, SPSS, Inc). Prognostic factors were analyzed using chi2 test. Survival analysis was estimated by the Kaplan-Meier method and compared using the log-rank test. Multivariate analysis was carried out by Cox regression.
RESULTSThe overall 1-, 3- and 5-year survival of these 67 patients was 71.0%, 18.7% and 9.2%, respectively. Univariate analysis revealed that the metastasis was confined in the ovary or pelvis only, unilateral/double ovarian metastasis, and operation mode were all statistically significant prognostic factors (P <0.05). Cox regression analysis showed that the operation mode was the most important prognostic factor (OR = 3.531, P <0.001).
CONCLUSIONSurgical treatment is still the most effective mode in the treatment for the ovary metastasis from colorectal cancer.
