Chemical constituents of flavonoids from rhizome of Sophora tonkinensis.

Author: Xingnuo LI ¹ ; Haixia YAN ; Xiaoyan PANG ; Na SHA ; Huiming HUA ; Lijun WU ; De'an GUO
Author Information

1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
Publication Type:Journal Article
MeSH: Chromatography, High Pressure Liquid; Flavonoids; analysis; chemistry; Genistein; analysis; Isoflavones; analysis; Rhizome; chemistry; Sophora; chemistry
From: China Journal of Chinese Materia Medica 2009;34(3):282-285
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo study the chemical constituents of the flavonoids from Sophora tonkinensis.
METHODThe compounds were isolated by chromatography on silica gel, Sephadex LH-20 column and identified by spectroscopic analysis.
RESULTEight compounds were isolated and their structures were identified as tonkinochromane I (1), glabrol (3), lupinifolin (2), tonkinensisol (4), 8-C-prenylkaempferol (5), 7,2'-dihydroxy-4'-methoxy-isoflavanol (6), formononetin (7), and genistein (8), respectively.
CONCLUSIONCompound 1 was a new compound. And compound 6 was firstly isolated from the genus Sophora. Compounds 2, 3 and 5 were isolated from S. tonkinensis for the first time.