Chemical constituents in roots of Osbeckia opipara.
- Author:
Hongsheng WANG
1
;
Yuehu WANG
;
Yana SHI
;
Xingyu LI
;
Chunlin LONG
Author Information
- Publication Type:Journal Article
- MeSH: Cholestenones; chemistry; isolation & purification; Fermentation; Fruiting Bodies, Fungal; chemistry; Melastomataceae; chemistry; Molecular Structure; Plant Extracts; chemistry; Plant Roots; chemistry; Spectrum Analysis; Triterpenes; chemistry; isolation & purification
- From: China Journal of Chinese Materia Medica 2009;34(4):414-418
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo study the chemical constituents of the roots of Osbeckia opipara.
METHODRepeated column chromatography over silica gel, RP-18 and Sephadex LH-20, and preparative thin layer chromatography(PTLC) were used to isolate the compounds, whose structures were determined by spectroscopic methods by direct comparing spectral data with those reported references.
RESULTFrom the MeOH extract of the roots O. opipara, twelve compounds were isolated and identified as follows: lasiodiplodin (1) , de-O-methyllasiodiplodin (2), 2, 3- dihydro-2-hydroxy-2, 4-dimethyl-5-trans-propenylfuran-3-one (3), integracin (4), 5alpha, 8alpha-epidioxy-(22E, 24R)-ergosta-6, 22-dien-3beta-ol (5), 3, 3', 4'-tri-O-methylellagic acid (6), 5-hydroxymethyl furaldehyde (7), vomifolio (8) , betulintic acid (9), 2alpha-hydroxyursolic acid (10), (24R)-stigmast-4-ene-3-one (11), and eugenitin (12).
CONCLUSIONCompounds 1-12 were isolated from O. opipara for the first time.
