A case-crossover study on air pollutants and the mortality of stroke
10.3321/j.issn:0254-6450.2008.09.007
- VernacularTitle:大气颗粒物污染与脑卒中死亡的病例交叉研究
- Author:
Yan-Jun REN
1
;
Xiu-Yang LI
;
Kun CHEN
;
Qing-Min LIU
;
Hai-Qing XIANG
;
Da-Feng JIN
;
Ren-Hua CHEN
Author Information
1. 杭州市疾病预防控制中心
- Keywords:
Stroke;
Particulate matter;
Air pollution;
Case-crossover study;
Time-stratification
- From:Chinese Journal of Epidemiology
2008;29(9):878-881
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the short-term effect of particulate matter in air on the mortality of stroke. Methods Using time-stratified case-crossover study design,an association was examined between stroke mortality and particulate matter with aerodynamic diameter of ＜10μm(PM10) of 2002- 2004 in Hangzhou city.Meanwhile,the acute health effect of other gaseous pollutants (sulfur dioxide,SO2 and nitrogen dioxide,NO2) was also analyzed.Results A total of 9906 deaths of stroke were included.The crude stroke mortality was 83.54 per 100 000.After being adjusted for meteorological factors,when an increase of 10 μg/m3 in PM10,SO2 and NO2 in three days was noticed,it appeared that the increases of mortality of stroke were 0.56%(95%CI:0.14%-0.99%),1.62%(95%CI:0.26%-3.01%) and 2.07%( 95%CI:0.54%-3.62%) respectively.There was no distinct association in multipollutant models.In sensitivity analysis,the associations were found in all single-pollutant models but not statistically significant in multi-pollutant models after replacing the missing values.Conclusion It is suggested that the short-term elevation in PM10 as well as SO2 and NO2 daily concentrations were related to the increase of stroke mortality in Hangzhou city.
