An Early Comparative Analysis of the Use of Autograft Versus Allograft in Anterior Cervical Discectomy and Fusion.
10.14245/kjs.2012.9.3.142
- Author:
Sang Yong KIM
1
;
Ki Seok PARK
;
Sung Sam JUNG
;
Seong Young CHUNG
;
Seong Mim KIM
;
Moon Sun PARK
;
Han Kyu KIM
Author Information
1. Department of Neurosurgery, Eulji University College of Medicine, Daejeon, Korea. ks3432@eulji.ac.kr
- Publication Type:Original Article
- Keywords:
Cervical Vertebrae;
Spinal Fusion;
Autograft;
Allograft
- MeSH:
Cervical Vertebrae;
Diskectomy;
Female;
Follow-Up Studies;
Humans;
Retrospective Studies;
Spinal Fusion;
Transplantation, Homologous;
Transplants
- From:Korean Journal of Spine
2012;9(3):142-146
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: The purpose of this study is to verify the usefulness of autograft versus allograft in the radiographic and clinical outcome in early period after the surgery. METHODS: We performed a retrospective review of 38 patients who had undergone one- or two-level anterior cervical discectomy and fusion (ACDF) with rigid anterior plate fixation from March 2006 to May 2009. Interbody graft materials were iliac autograft (n=17) or with allograft (n=21). Fusion rate and graft collapse rate were assessed by radiographic analysis and clinical outcome was based on Odom's criteria. RESULTS: In autograft group, 13 patients achieved successful bone fusion (65%), whereas 7 patients (31.8%) in allograft group. There was statistically significant between two groups (p<0.05). Comparing immediate postoperative radiograph with last follow-up, the mean graft collapse was noted 1.3mm(15.5% change) in autograft group, whereas 2.0mm(24.7% change) in allograft group. There was no statistically significant collapse rate in autograft group (p>0.05), but statistically significant in allograft group (p<0.05). Clinical outcome was excellent or good in 94.1% in autograft group, and 90.5% in allograft group. CONCLUSION: In study, anterior cervical interbody fusion with an allograft got a result of lower fusion rate and higher collapse rate compared with autograft in early period after surgery, and clinical outcome showed similar results in both groups.
