Levels of transition on maternal transferred measles antibody in infants in 3 cities in China
10.3321/j.issn:0254-6450.2008.11.005
- VernacularTitle:中国三城市麻疹母婴配对及小月龄母传抗体水平消长研究
- Author:
Guo-Zhang XU
1
;
Rui MA
;
Hong-Jie XU
;
Yan-Hui MA
;
Hong-Jun DONG
;
Yan LI
;
Feng-Xia HU
;
Hong-Xia NI
;
Guo-Lin BIAN
;
Ying LIANG
;
Lan-Zheng LIU
;
Shao-Ying ZHOU
;
Qing-Jie HUAI
;
Xiu-Yun HAN
Author Information
1. 宁波市疾病预防控制中心
- Keywords:
Measles;
Infant;
Epidemiological characteristics;
Maternal-transferred antibody
- From:Chinese Journal of Epidemiology
2008;29(11):1074-1077
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the epidemiological characteristics of age distribution of measles and related policies on measles vaccines (live; MV) in infants through analyzing the antibody levels of comparison in maternal-infant pairs. Transition of immunity in infants was also studied to provide theoretic basis for measles immunization strategy and to reduce the incidence of month-old infants. Methods In cities of Ningbo, Harbin, and Jinan from Zhejiang, Heilongiiang and Shandong provinces, data was collected from 2004 to 2007 and analyzed regarding the epidemic situation of measles. Studies on maternal-transferred measles antibody were carried our sero-epidemiologically. Results Most of the measles cases were found among babies younger than 12 months,and the incidence of < 1 year olds had been increasing.The distribution was dominated by 5-8 month olds in infant measles cases. The positive rate and GRMT of measles antibody in newborns were 89.3 percent and 738.93. The positive rate of the measles antibody and GMRT of the 6-month infant were 6.9 % and 6.89, while 6.7 % and 3.69 in 8-month infant. There wasa declining trend of the positive rate of the measles antibody during the newborns to 8-month infant. The positive rate and GRMT of measles antibody in mothers were 84.3 percent and 516.94. Mother's measles antibodies mainly to be at low and moderate level, which accounted for 50.4 percent and 30.3 percent respectively, the correlation coefficient between mother and infant was 0. 840. Conclusion Maternal-transferred measles antibody decreased as the growth of infants. The positive rates of measles antibody were quite low in 6-month and 8-month olds which were the age range that needs most attention.
