Study on the changes of incidence rates on birth defects through hospital based surveillance program in Guangdong province during 1997-2007
10.3321/j.issn:0254-6450.2008.11.011
- VernacularTitle:广东省1997-2007年医院监测出生缺陷趋势分析
- Author:
Bing LI
1
;
Xiao-Zhuang ZHANG
;
Ning YE
;
Li MU
;
Jian-Hong XIA
;
Xiu-Jian HUANG
;
Shao-Lan HE
Author Information
1. 广东省妇幼保健院
- Keywords:
Birth defects;
Surveillance;
Perinatal infant
- From:
Chinese Journal of Epidemiology
2008;29(11):1101-1105
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the tendency of hospital based surveillance incidence rates of birth defects in Guangdong province to provide reference evidence for related intervention program. Methods Data from hospital based birth defects surveillance of Guangdong province during 1997-2007 were analyzed retrospectively. Results The overall surveillance rates of birth defects in Guangdong province showed an increasing trend form 98.9 per 10 000 birth in 1997 to 244.2 per 10 000 birth in 2007. Among the frequently seen birth defects, the rate of congenital heart diseases increased sharply, but the rates of congenital talipes equinovarus, polydactyly, cleft lip with/without cleft palate showed a slight increasing trend.It seemed that there was a significant difference between different maternal age interval and gender of the infants. Mother's illness, drug use, and exposure to environment harmful factors in early pregnancy stage, high maternal age, negative bearing history were the suspect risk factors for birth defects. Conclusion The increasing trend of surveillance rate of birth defects seemed to be comprehensively affected by the factors as: method being adopted, target and extension of birth defects surveillance, technology used for diagnosis, kinds of risk factor,and quality control on surveillance programs.
