Cellular compatibility of type collagen I scaffold and human adipose-derived stem cells.
- Author:
Yun-Song ZHANG
1
;
Jian-Hua GAO
;
Feng LU
;
Ming ZHU
;
Yun-Jun LIAO
Author Information
- Publication Type:Journal Article
- MeSH: Adipocytes; cytology; Adult Stem Cells; cytology; Biocompatible Materials; chemistry; Cells, Cultured; Coculture Techniques; Collagen Type I; chemistry; Humans; Tissue Engineering; methods; Tissue Scaffolds
- From: Journal of Southern Medical University 2007;27(2):223-225
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the cellular compatibility of type I collagen scaffold and human adipose-derived stem cells (ADSC(S)) in order to explore appropriate scaffold materials for adipose tissue engineering.
METHODSThe morphology and function of the ADSC(S) were observed by inverted phase contrast microscope, scanning electron microscope and XTT assay when cocultured type I collagen scaffold with ADSC(S) in vitro. Cells adhesive rates were also calculated.
RESULTADSC(S) were able to attach, grow and proliferate well on the scaffolds.
CONCLUSIONcollagen I scaffold exhibits excellent cellular compatibility and can be used as a vehicle for adipose tissue engineering.
