Chemical constituents of the non-alkaloid fraction of Uncaria macrophylla.
- Author:
Jun-Yan WU
1
;
Guo-Cheng LI
;
Ding-Yong WANG
Author Information
- Publication Type:Journal Article
- MeSH: Oleanolic Acid; analogs & derivatives; isolation & purification; Triterpenes; isolation & purification; Uncaria; chemistry
- From: Journal of Southern Medical University 2007;27(2):226-227
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze the chemical constituents of the non-alkaloid fraction of Uncaria macrophylla.
METHODSThe constituents were separated and purified by silica gel chromatography and recrystalization, and their structures were identified by infrared, mass and nuclear magnetic resonance spectrometry.
RESULTSSix compounds were isolated from the non-alkaloid fraction of Uncaria macrophylla, whose structures were identified as beta-sitosterol, beta-daucosterol, ursolic acid, alpha-amyrin acetate, 3beta, 6beta, 23-trihydroxyurs-12-en-28-oic acid, 3beta-hydroxyurs-12-en-27, and 3beta-hydroxyurs-12-en-27, 28-dioic acid, respectively.
CONCLUSIONSUrsolic acid is the main component in the non-alkaloid fraction of Uncaria macrophylla. Alpha-amyrin acetate and 3beta-hydroxyurs-12-en-27, 28-dioic acid are isolated and characterized for the first time from this plant.
