Metabolites from the endophytic fungus Penicillium sp. FJ-1 of Ceriops tagal.
- Author:
Peng-fei JIN
1
;
Wen-jian ZUO
2
;
Zhi-kai GUO
2
;
Wen-li MEI
2
;
Hao-fu DAI
2
Author Information
1. College of Environment and Plant Protection, Hainan University, 570228 Haikou, China.
2. Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, 571101 Haikou, China.
- Publication Type:Journal Article
- MeSH:
Anti-Bacterial Agents;
chemistry;
isolation & purification;
pharmacology;
Flavones;
chemistry;
isolation & purification;
pharmacology;
Methicillin-Resistant Staphylococcus aureus;
drug effects;
Molecular Structure;
Penicillium;
chemistry;
isolation & purification;
Rhizophoraceae;
microbiology;
Staphylococcus aureus;
drug effects
- From:
Acta Pharmaceutica Sinica
2013;48(11):1688-1691
- CountryChina
- Language:English
-
Abstract:
To investigate the chemical constituents of the endophytic fungus Penicillium sp. FJ-1 of Ceriops tagal, the chemical constituents were isolated by column chromatography on silica gel and Sephadex LH-20. Their structures were elucidated on the basis of spectroscopic analysis. Their antibacterial activity was tested by paper disco diffusion method. Two compounds were isolated and identified as 7-hydroxy-deoxytalaroflavone (1), and deoxytalaroflavone (2). Compound 1 is a new compound, and compounds 1 and 2 showed weak activity against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus.
