Expression of kinase insert domain-containing receptor in prostate adenocarcinoma.
- Author:
An-sheng BAI
1
;
Hao ZENG
;
Xiang LI
;
Qiang WEI
;
Hong LI
;
Yu-ru YANG
Author Information
- Publication Type:Journal Article
- MeSH: Adenocarcinoma; metabolism; Humans; Male; Prostatic Hyperplasia; metabolism; Prostatic Neoplasms; metabolism; Receptors, Vascular Endothelial Growth Factor; biosynthesis; Vascular Endothelial Growth Factor Receptor-2; biosynthesis
- From: National Journal of Andrology 2007;13(4):324-326
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the correlation between the expression of the kinase insert domain-containing receptor (KDR) and the histological grade of prostate adenocarcinoma.
METHODSForty-eight samples of prostate adenocarcinoma tissues and 20 samples of benign prostatic hypertrophy (BPH) tissues were studied by LsAB immunohistochemical staining.
RESULTSThe positive expression rate of KDR was 73% in prostate adenocarcinoma and 30% in BPH. The expression of KDR was stronger in prostate adenocarcinoma, and there was no relationship between staining intensity and the histological grade of carcinoma.
CONCLUSIONKDR, expressed more highly in prostate adenocarcinoma, promises to be a new target in the treatment of prostate adenocarcinoma.
