Diffusion weighted imaging: its diagnostic and differential value for prostate cancer.
- Author:
Hao SHI
1
;
Hong-Yu DING
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; instrumentation; methods; Humans; Male; Middle Aged; Prostate; pathology; Prostatic Neoplasms; diagnosis; Reproducibility of Results; Sensitivity and Specificity
- From: National Journal of Andrology 2007;13(7):605-609
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the diagnostic and differential value of diffusion weighted imaging (DWI) for prostate cancer.
METHODSIncluded in the study were 50 patients with prostatic diseases, including 19 cases of prostate cancer (PCa) and 31 cases of benign prostatic hyperplasia (BPH), and another 16 healthy volunteers were recruited as controls. All underwent DWI sequence on a 1.5T superconducting MRI system with an endorectal coil. The results from DWIs and apparent diffusion coefficient (ADC) maps were treated statistically.
RESULTSThe mean ADC value of the prostatic peripheral zone and the prostatic central gland of the 16 healthy volunteers were (170.23 +/- 37.39) x 10(-5) mm2/s and (127.84 +/- 17.93) x 10(-5) mm2/s, while those of the 31 BPH cases and 19 PCa cases were (175.21 +/- 64.86) x 10(-5) mm2/s and (104.23 +/- 26.15) x 10(-5) mm2/s, respectively. There were significant differences in the tissue types between any two groups after the treatment of one-way ANOVA, except between the groups of the peripheral zone and. BPH.
CONCLUSIONPCa shows specific DWI features that could be distinguished from those of the normal prostatic tissues and BPH. Therefore, DWI has an important clinical application value in the diagnosis and differentiation of PCa.
