Tentative trial of antibiotic combination in the liquid medium for antibiotic resistance Staphylococcus aereus
- Author:
Xuan Thi Thanh Do
- Publication Type:Journal Article
- Keywords:
antibiotic
- MeSH:
Anti-Bacterial Agents;
Staphylococcus
- From:Journal of Practical Medicine
2002;435(11):13-14
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
To predict the potential therapeutic efficacy of combination of antibiotics, methods have been developed to quantitative their effects on bacterial growth in vitro. Two distinct different methods are used. The first methods for evaluating drug combinations involve quantitation on their rate of bactericidal action. The second employs serial twofold dilution of antibiotics in broth in osculated with a standard number of the test microorganism in a checkerboard fashion, so that antibiotic concentration in different proportion can be tested simultaneously. Laboratory trials have carried out on antimicrobe resistant S. anreus. We found that gentamicine combined penicillin or gentamycine combined cephalothin in more rapidly bactericidal effect than either drug alone, the result is termed synergism. On the contrary, antagonism in said to occur with penicillin combined chloramphenicol.
