Hypertension and intermittent convulsions for one month in a school-age child.
- Author:
Mao-Qiang TIAN
1
;
Shu-Yi LIU
;
Juan LI
;
Xiao-Mei SHU
Author Information
1. Department of Pediatrics, Affiliated Hospital of Zunyi Medical College, Zunyi, Guizhou 563003, China. shuxiaomei1993@sina.com.
- Publication Type:Case Reports
- MeSH:
Child;
Female;
Humans;
Hypertension;
etiology;
Polyarteritis Nodosa;
diagnosis;
Seizures;
etiology
- From:
Chinese Journal of Contemporary Pediatrics
2017;19(7):816-819
- CountryChina
- Language:Chinese
-
Abstract:
Childhood polyarteritis nodosa (PAN) is a rare systemic vasculitis and the delayed diagnosis and treatment will cause high incidence of sequelae and high mortality. This article reports a girl with childhood PAN due to posterior reversible encephalopathy syndrome (PRES). The girl aged ten years was admitted to the hospital due to hypertension and convulsions for one month. She had complaints of headache, vomiting, and blurred vision before convulsions. At six months before admission, a mass was observed in the neck. The physical examination showed that she had hypertension and no abnormal findings in the central nervous system. The brain magnetic resonance imaging manifested long T1 and T2 signals, high signal intensities on fluid-attenuated inversion recovery (FLAIR) images, and iso-signal intensity on diffusion-weighted imaging in the white matter of the left occipital lobe. Therefore, the cause of convulsions was considered as PRES. Mass biopsy suggested PAN and no findings supported tuberculosis. The right kidney atrophy was observed by ultrasound examination. Emission computed tomography of the kidney showed multiple vascular stenosis and no blood perfusion in the right kidney, so PAN was confirmed. These findings suggest that PAN should be considered in patients with vasculitis who had involvements of multiple systems after excluding common vasculitis, such as Kawasaki disease and Henoch-Schönlein purpura. Biopsy and angiography should be performed as early as possible for timely diagnosis and treatment.
