Reaction of epithelial cell rests of malassez to tooth emergence and occlusal function reaction of epithelial cell rests of Malassez to tooth emergence and occlusal function.
- Author:
Xi-jiao YU
1
;
Shu LI
;
Lan YU
;
Chang-jie XIAO
;
Zong-xia LIU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Apoptosis; Cell Proliferation; Epithelial Cells; Mice; Microscopy, Electron, Transmission; Molar; Periodontal Ligament; Rest; Tooth
- From: West China Journal of Stomatology 2007;25(6):599-602
- CountryChina
- Language:Chinese
-
Abstract:
UNLABELLEDOBJECTIVE To observe the morphology and proliferation of epithelial cell rests of Malassez (ECRM) during tooth emergence and occlusal function, and to evaluate its roles.
METHODSCytokeratin 14 (CK14) was applied as special marker of ECRM cells. The morphology and distribution of ECRM were examined by light and transmission electron microscopy. PV two-step immunohistochemical method was used to detect the expression of CK14 and proliferating cell nuclear antigen (PCNA) in ECRM.
RESULTSECRM experienced instinct morphological changes during tooth emergence and occlusal function. They were observed as network of epithelial cells labeled by CK14, especially in furcation level regions of mouse molars and active cell proliferation during occlusion found period. Cell apoptosis was observed in many ECRM by transmission electron microscopy during late stage of the progess.
CONCLUSIONECRM may not only an accidental left-over of early embryonic development but rather play significant roles in occlusion found period.
