Prevalence of High Non-high-density Lipoprotein Cholesterol and Associated Risk Factors in Patients with Diabetes Mellitus in Jilin Province, China: A Cross-sectional Study.
- Author:
Huan HE
1
;
Qing ZHEN
1
;
Yong LI
1
;
Chang Gui KOU
1
;
Yu Chun TAO
1
;
Chang WANG
1
;
Joseph Sam KANU
1
;
Yu Ping LU
1
;
Ming Xi YU
1
;
Hui Ping ZHANG
2
;
Ya Qin YU
1
;
Bo LI
1
;
Ya Wen LIU
1
Author Information
- Publication Type:Letter
- MeSH: Adolescent; Adult; China; epidemiology; Cross-Sectional Studies; Diabetes Mellitus; epidemiology; etiology; Female; Humans; Hypercholesterolemia; epidemiology; Male; Middle Aged; Prevalence; Risk Factors; Young Adult
- From: Biomedical and Environmental Sciences 2016;29(7):534-538
- CountryChina
- Language:English
- Abstract: Dyslipidemia is a risk factor for cardiovascular diseases (CVDs) in patients with diabetes, and non-high-density lipoprotein cholesterol (non-HDL-C) is a better predictor of CVDs than low-density lipoprotein cholesterol (LDL-C) in patients with diabetes. Therefore, we aimed to investigate the distribution of non-HDL-C and the prevalence of high non-HDL-C level in Chinese patients with diabetes mellitus and identify the associated risk factors. Non-HDL-C concentration positively correlated with total cholesterol, triglycerides, and LDL-C concentrations. Although both non-HDL-C and LDL-C concentration both related positively with TC concentration, the magnitude of correlation was relatively higher for non-HDL-C. The prevalence of high non-HDL-C (⋝4.14 mmol/L) was higher in two age groups (55-64 years: 46.7%; 65-79 years: 47.3%) than other age groups (18-24 years: 4.2%; 25-34 years: 43.6%; 35-44 years: 38.1%; 45-54 years: 41.0%). It was also higher among overweight (45.1%), generally obese (50.9%), or abdominally obese (47.3%) subjects, compared with normal weight subjects (34.5%). The risk of high non-HDL-C increased with advancing age. Both general obesity [odds ratio (OR)=1.488, 95% confidence interval (CI): 1.003-2.209] and abdominal obesity (OR=1.561, 95% CI: 1.101-2.214) were significantly associated with high non-HDL-C levels.
