The Genomic Characterization of Enterovirus D68 from 2011 to 2015 in Beijing, China.

Author: Tie Gang ZHANG ¹ ; Hong Quan LI ¹ ; Ai Hua LI ¹ ; Meng CHEN ¹ ; Cheng GONG ¹ ; Ming LUO ¹ ; Mei DONG ¹ ; Fang HUANG ¹
Author Information

1. Beijing Center for Disease Prevention and Control, Beijing 100013, China.
Publication Type:Journal Article
MeSH: Adolescent; Aged; Beijing; epidemiology; Child; Child, Preschool; Enterovirus D, Human; classification; genetics; isolation & purification; Enterovirus Infections; epidemiology; virology; Female; Genome, Viral; Humans; Male; Phylogeny; Retrospective Studies
From: Biomedical and Environmental Sciences 2016;29(9):675-677
CountryChina
Language:English
Abstract: A retrospective surveillance study on enterovirus D68 was performed in Beijing, China, following the largest and most widespread EV-D68 infection, which occurred in the USA. From January 2011 to July 2015, EV-D68 was identified in 12 individuals with respiratory infections in Beijing, China. The phylogenetic relationships based on the genomic sequence alignment showed that there were two lineages circulating in Beijing from 2011 to 2015. Eight EV-D68 strains belonged to group 1 and four belonged to group 3. All EV-D68 strains from Beijing in 2014 were separately clustered into subgroup II of group 1. Based on these results, we concluded that the Beijing EV-D68 strains had little association with the EV-D68 strains circulating in the 2014 USA outbreak.