BMI and BMI Changes to All-cause Mortality among the Elderly in Beijing: a 20-year Cohort Study.

Yun Feng WANG; Zhe TANG; Jin GUO; Li Xin TAO; Long LIU; Hai Bin LI; Di Tian LI; Xiu Hua GUO; Xing Hua YANG

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BMI and BMI Changes to All-cause Mortality among the Elderly in Beijing: a 20-year Cohort Study.

Author: Yun Feng WANG ^{1
,

2} ; Zhe TANG ³ ; Jin GUO ¹ ; Li Xin TAO ¹ ; Long LIU ¹ ; Hai Bin LI ¹ ; Di Tian LI ⁴ ; Xiu Hua GUO ¹ ; Xing Hua YANG ¹ ;
Author Information

1. School of Public Health, Capital Medical University, Beijing 100069, China
2. Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing 100069, China.
3. Xuan Wu Hospital, Capital Medical University, Beijing 100053, China.
4. School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Publication Type:Journal Article
Keywords: All-cause mortality; Beijing; Body mass index; The elderly
MeSH: Aged; Aged, 80 and over; Beijing; Body Mass Index; Chronic Disease; mortality; Cohort Studies; Female; Humans; Male; Middle Aged; Proportional Hazards Models; Risk Factors
From: Biomedical and Environmental Sciences 2017;30(2):79-87
CountryChina
Language:English
Abstract:
OBJECTIVETo explore the association between body mass index (BMI) and all-cause mortality among the elderly in Beijing.
METHODSThis analysis was based on the Beijing multidimensional longitudinal study of aging (BLSA), which included 2,090 subjects over 55 years old and was followed-up from 1992 to 2012. BMI-mortality curves were drawn to find the optimal BMI range with the lowest mortality. Cox proportional hazard models were used to obtain the hazard ratios (HRs) for BMI and BMI changes in the overall population and in specific stratified populations.
RESULTSDuring follow-up, 1,164 deaths were recorded; BMI-mortality curve was U-shaped, with the lowest mortality at a BMI of approximately 25 kg/m2. After adjusting for gender, age, smoking, drinking and some pre-existing diseases, HRs for underweight, overweight and obesity compared with normal weight were 1.372 (95% CI: 1.154-1.631), 0.767 (95% CI: 0.666-0.884) and 0.871 (95% CI: 0.830-1.246), respectively. HR for BMI drop was 3.245 (95% CI: 0.824-12.772) in the underweight group and 1.892 (95% CI: 0.830-1.246) in the normal weight group, HR for BMI rise was 1.795 (95% CI: 1.243-2.591) in normal weight group and 1.962 (95% CI: 1.202-3.203) in the overweight group.
CONCLUSIONKeeping BMI in an overweight status and stable is related to a reduced mortality.