Unusual Case of Posterior Reversible Encephalopathy Syndrome in a Patient with Anti-glomerular Basement Membrane Antibody Glomerulonephritis: A Case Report and Review of the Literature.
- Author:
Boram CHA
1
;
Dae Young KIM
;
Hyunil JANG
;
Seun Deuk HWANG
;
Huck Jei CHOI
;
Moon Jae KIM
Author Information
- Publication Type:Case Report
- Keywords: Posterior reversible encephalopathy syndrome; Anti-glomerular basement membrane antibody glomerulonephritis; Hypertension; Cyclophosphamide
- MeSH: Adult; Autoimmune Diseases; Basement Membrane*; Blindness; Brain; Consciousness; Cyclophosphamide; Edema; Female; Glomerulonephritis*; Headache; Humans; Hypertension; Hypertension, Renal; Immunosuppression; Infarction; Magnetic Resonance Imaging; Parietal Lobe; Posterior Leukoencephalopathy Syndrome*; Renal Dialysis; Renal Insufficiency; Seizures; Strikes, Employee
- From:Electrolytes & Blood Pressure 2017;15(1):12-16
- CountryRepublic of Korea
- Language:English
- Abstract: Posterior reversible encephalopathy syndrome (PRES) is characterized by a clinical and radiological entity with the sudden onset of seizures, headache, altered consciousness, and visual disturbances in patients with the findings of reversible vasogenic subcortical edema without infarction. Hypertension, renal disease, and autoimmune disease are co-morbid conditions of PRES. Nevertheless, there have only been a few case reports of PRES in a patient with anti-glomerular basement membrane antibody glomerulonephritis (anti-GBM GN). This paper presents the possible first Korean case of a 36-year-old woman with the striking features of PRES. She presented with a sudden onset of visual blindness, headache, and seizure. The brain MRI images revealed hyperintense lesions in both the occipital and parietal lobes, which suggested vasogenic edema. Three months before this presentation, she was diagnosed with anti-GBM GN. Since then, she underwent immunosuppression with cyclophosphamide and steroid, and hemodialysis for renal failure with a treatment of anti-GBM GN.
