Chronic Hepatitis E Virus Infection and Treatment in Organ Transplant Recipients.
- Author:
Shu CHEN
;
Feixue WEI
;
Ting WU
;
Ningshao XIA
- Publication Type:Journal Article
- MeSH:
Animals;
Antiviral Agents;
therapeutic use;
Hepatitis E;
drug therapy;
virology;
Hepatitis E virus;
genetics;
isolation & purification;
physiology;
Hepatitis, Chronic;
drug therapy;
virology;
Humans;
Transplant Recipients;
Transplants;
virology
- From:
Chinese Journal of Virology
2015;31(3):293-298
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis E, caused by hepatitis E virus (HEV) infection, usually leads to an acute clinical course, and is the most common diagnosis among cases of acute viral hepatitis. From 2008, there have been increasing reports of chronic HEV infection in immunocompromised patients such as organ transplant recipients. Without intervention with antiviral treatment, approximately 60% of HEV infections in organ transplant recipients evolve into chronic HEV infections. Of these chronic hepatitis E patients, 10% may develop liver fibrosis and progress to liver cirrhosis. This article reviews chronic HEV infection and treatment in organ transplant recipients.
