Advances in Correlation between Rotaivrus and Histo-blood Group Antigens.
- Author:
Dandi LI
;
Sun XIAOMAN
;
Zhaojun DUAN
- Publication Type:Journal Article
- MeSH:
Animals;
Blood Group Antigens;
genetics;
immunology;
Genetic Variation;
Humans;
Rotavirus;
immunology;
physiology;
Rotavirus Infections;
blood
- From:
Chinese Journal of Virology
2015;31(4):463-467
- CountryChina
- Language:Chinese
-
Abstract:
Group A rotaviruses (RVs) are major pathogens associated with acute gastroenteritis in young children and animals worldwide. VP4 is responsible for interaction with the host and viral attachment. Recent study showed that the distal portion of rotavirus (RV) VP4 spike protein (VP8*) is implicated in binding to human histo-blood group antigens (HBGAs), which is new cellular receptors on rotavirus, Published in Nature and Journal of Virology in 2012. The paper describes advances in correlation between rotaivrus and HBGAs, summarizes the main achievements has gotten, Clarify the significance of study on Rotaivrus and HBGAs.
