The Role of fluorodeoxyglucose PET in the management of breast cancer.
- Author:
Won Hyoung LEE
1
;
Ie Ryung YOO
Author Information
1. Department of Radiology, College of medicine, The Catholic University of Korea. iryoo@catholic.ac.kr
- Publication Type:Review
- Keywords:
FDG PET;
breast cancer;
staging;
recurrence;
monitoring of response
- MeSH:
Breast Neoplasms*;
Breast*;
Diagnosis;
Drug Therapy;
Humans;
Lymph Nodes;
Neoplasm Metastasis;
Recurrence
- From:Hanyang Medical Reviews
2007;27(4):43-51
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In breast cancer, FDG PET is more accurate than conventional imaging methods for detecting distant metastases or local recurrences, and enables early ssessment of treatment response in patients undergoing primary chemotherapy. Though FDG PET has limited sensitivity in detecting tumor of small size, well differentiated tumor or lobar carcinoma, and regional lymph node metastasis, FDG PET is useful in cases with obscure MR images and axillary lymph node metastasis in locally advanced breast cancer. To minimize the side effects and cost of chemotherapy, imaging methods are required to monitor theresponse to chemotherapy, early and accurately. FDG PET is the appropriate method for this purpose. We reviewed the role of FDG-PET in diagnosis and initial staging of breast cancer, monitoring response to chemotherapy, and identifying metastatic and recurrent disease.