Research Advances in Target Genes of Epstein-Barr Virus-encoded MicroRNAs.
- Author:
Liwei GAO
;
Junhong AI
;
Zhengde XIE
;
Kunling SHEN
- Publication Type:Journal Article
- MeSH:
Animals;
Epstein-Barr Virus Infections;
genetics;
metabolism;
virology;
Herpesvirus 4, Human;
genetics;
physiology;
Humans;
MicroRNAs;
genetics;
metabolism;
RNA, Viral;
genetics;
metabolism
- From:
Chinese Journal of Virology
2016;32(2):229-234
- CountryChina
- Language:Chinese
-
Abstract:
The Epstein-Barr virus (EBV) is a gamma herpes virus associated with several types of malignancies. The EBV encodes viral microRNAs (miRNAs) that can target genes within cells. The EBV participates in signal transduction as well as the proliferation and differentiation of cells. How the target genes and functions of EBV-encoded miRNAs contribute to the pathogenesis of EBV is an important research topic. Some target genes have been validated since EBV-encoded miRNAs were discovered and, in this article, we summarize them and their functions.
