- VernacularTitle:CD4+/CD8-T-大颗粒淋巴细胞白血病一例报告并文献复习
- Author:
Yang LI
1
;
Zhijie WU
1
;
Jianping LI
1
;
Yuan LI
1
;
Guangxin PENG
1
;
Lin SONG
1
;
Wenrui YANG
1
;
Kang ZHOU
1
;
Li ZHANG
1
;
Liping JING
1
;
Fengkui ZHANG
1
Author Information
- Publication Type:Case Reports
- MeSH: Anemia; Humans; Immunophenotyping; Leukemia, Large Granular Lymphocytic; classification; diagnosis
- From: Chinese Journal of Hematology 2015;36(9):739-742
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEPresenting the clinical features of one patient with CD4⁺/CD8⁻ T-cell large granular lymphocytic leukemia, to improve the understanding of the disease.
METHODSClinical data of one patient hospitalized for skin rush and leukocytosis were analyzed, and the related literatures were reviewed.
RESULTSThe patient was hospitalized for skin rush and leukocytosis. Routine blood test showed remarkable elevated white blood cell counts and mild anemia. Subsequent hematological examination led to a diagnosis of T- cell large granular lymphocytic leukemia with CD4⁺/CD8⁻ immunophenontype.
CONCLUSIONCD3⁺/CD4⁺/CD8⁻ T- cell large granular lymphocytic leukemia is a kind of variant subtype, and is relatively rare, it has different clinical features with classic CD3⁺/CD4⁻/CD8⁺/TCRαβ⁺T- cell large granular lymphocytic leukemia, so differentiating diagnosis is of great importance.