Reproducibility of the negative expiratory pressure technique in detecting expiratory flow limitation on chronic obstructive pulmonary disease patients
10.3760/cma.j.issn.0254-6450.2010.12.016
- VernacularTitle:呼气负压技术检测慢性阻塞性肺疾病患者呼气气流受限的可重复性分析
- Author:
Rui CHEN
1
;
Lian CHEN
;
Rong-Chang CHEN
;
Xin CHEN
Author Information
1. 中山大学附属第二医院
- Keywords:
Pulmonary disease,chronic obstructive;
Dyspnea;
Expiratory flow limitation
- From:
Chinese Journal of Epidemiology
2010;31(12):1397-1399
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the reproducibility of Negative Expiratory Pressure(NEP)technique in detecting expiratory flow limitation (EFL) on chronic obstructive pulmonary disease (COPD) patients. Methods EFL was evaluated with NEP technique in 72 subjects having stable COPD on two occasions. Agreement between testing occasions was assessed with the κ statistic for the 3-point and 5-point EFL scores, and with paired t-test for FL index. Results On the first testing occasion, 18 subjects had no EFL, 18 subjects had EFL in the supine position, and 36 subjects in the sitting and the supine position. Using the 3-point score, agreement was present in 58 of the 72 subjects at time 2 (κ =0.69, P<0.001 ), indicating a substantial agreement was found. Using the 5-point score, agreement was seen in 52 of the 72 subjects (κ =0.65, P<0.001 ), also indicating a substantial agreement. The difference of FL index between the first and the second occasion was significant in both the sitting (P<0.05) and supine (P<0.05) positions. Conclusion Both 3-point and 5-point scores provided a reproducible assessment of EFL on COPD patients but the FL index seemed less reproducible. More research were needed before NEP technique was promoted to be used clinically.