Investigation on an outbreak of measles caused by new virus (d11 genotype) imported from Myanmar
10.3760/cma.j.issn.0254-6450.2011.01.005
- VernacularTitle:一起缅甸输入新型麻疹病毒(d11基因型)引发暴发疫情的调查分析
- Author:
Yan-Kun PANG
1
;
Li-Qun LI
;
Zheng-Rong DING
;
Min PENG
;
Yuan-Qing ZHU
;
Zheng-You WANG
;
Yan LI
Author Information
1. 云南省疾病预防控制中心
- Keywords:
Measles virus;
Outbreak;
Myanmar input
- From:
Chinese Journal of Epidemiology
2011;32(1):17-19
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relevant factors on an measles outbreak caused by imported new virus (d11 genotype)from Myanmar and to develop effective strategies and measures.Methods On-site investigation on the outbreak was carried out. Results There were four townships (66%) in Menglian county reported 15 cases of measles, with 7 cases aged 6 months to 5 years old, 2 cases with the history of measles vaccination (MV). Another 8 cases were 21 to 49 year-olds but their histories on immunization were unclear. 14 of the measles cases with Myanmar citizenship came to China for treatment. They were aged 10 months to 13 years old, with only one case had ever received MV vaccination. For all the 29 cases, except for one case who did not adopt the sample case of Myanmar, the remaining 28 patients were positive for measles IgM antibodies. 6 cases of measles virus RNA were detected in the amplified sequence which showed genotype d11, and was considered Myanmar imported wild virus. 184 people received the MV inoculation, with a rate of 61.96% and the serum samples showed a measles IgG antibody positive rate of 87.50%. Manner MV emergency vaccination was carried out timely in that county so the measles outbreak was effectively controlled.Conclusion Imported measles cases from foreign countries might lead to epidemic, indicating the difficulty and challenge in the elimination of measles in our province. Emergent vaccination of MV could interrupt the transmission of the disease. Our experience showed that MV was effective in the prevention of d11 genotypes measles infection in the area.
