Study on anti-diabetes active fraction and constituents from Potentilla chinesis.
- Author:
Chuan ZHAO
1
;
Wei QIAO
;
Yan-Wen ZHANG
;
Bin LU
;
Hong-Quan DUAN
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Blood Glucose; metabolism; Diabetes Mellitus, Experimental; blood; drug therapy; Drugs, Chinese Herbal; chemistry; pharmacology; therapeutic use; Female; Flavones; Flavonoids; pharmacology; Hypoglycemic Agents; chemistry; pharmacology; therapeutic use; Male; Mice; Potentilla; chemistry
- From: China Journal of Chinese Materia Medica 2008;33(6):680-682
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the active fraction and constituents from Potentilla chinesis.
METHODTested fractions were obtained by different solvent-partition from 95% ethanol-extracts of P. chinesis, and tested compound was isolated by repeated chromatography. Anti-diabetes experiment was taken by using alloxan-induced diabetic mice.
RESULTThe fraction F and the tested compound revealed obvious difference comparing with the control group (P <0.01).
CONCLUSIONFraction F and potentilla flavone revealed the significant hypoglycemic effect in alloxan-induced diabetic mice.
