A new flavonoid from heartwood of Caesalpinia sappan.

Author: Shi-Hui SHU ¹ ; Jing-Lan HAN ; Guan-Hua DU ; Hai-Lin QIN
Author Information

1. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Bioactive Substances and Resources of Chinese Herbal Medicine, Ministry of Education, Beijing 100050, China.
Publication Type:Journal Article
MeSH: Animals; Caesalpinia; chemistry; Cell Line, Tumor; Cell Proliferation; drug effects; Drugs, Chinese Herbal; chemistry; Flavonoids; isolation & purification; pharmacology
From: China Journal of Chinese Materia Medica 2008;33(8):903-905
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo seek for new active components from Caesalpinia sappan.
METHODThe chemical constituents were isolated and identified by means of chromatographic and spectroscopic technologies methods.
RESULTNine compounds were isolated, and their structures were identified as 3, 8-dihydroxy4, 10-dimethoxy-7-oxo-[2] benzopyrano[4,3-b] benzopyran (1), 3-deoxysappanchalcone (2), sappanchalcone (3), 3-deoxysappanone B (4), rhamnetin (5), protosappanin C (6), 3, 7-dihydroxy-chroman-4-one (7), dimethyl adipate (8), daucosterin (9).
CONCLUSIONCompound 1 was a new compound, and compounds 7, 8 were isolated from this plant for the first time.