Study on the solubilization of O/W microemulsion for volatile oil.
- Author:
Hong YI
1
;
Hua YANG
;
Mao DENG
Author Information
- Publication Type:Journal Article
- MeSH: Drugs, Chinese Herbal; chemistry; Emulsions; Oils, Volatile; chemistry; Solubility; drug effects; Surface-Active Agents; pharmacology; Water; chemistry
- From: China Journal of Chinese Materia Medica 2008;33(11):1259-1263
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the solubilization of O/W microemulsion system for volatile oil.
METHODPseudo-ternary phase diagrams were prepared by using the method of titration, then investigating the solubilization of microemulsion system for different kind of volatile oil was investigated with the diagrams, and the effect of the formulation of microemulsion on the solubilization of Citrus sinensis oil were studied.
RESULTKinds of volatile oil have an accelerated solubility in the microemulsion system. The species and dosage of oil phase and surfactant could influence the solubilization of microemulsion on Citrus sinensis oil.
CONCLUSIONIt is recommended to select a new method to solve the stabilization of volatile oil in the liquid preparation by the solubilization of suitable formulation of microemulsion.
