Association between microalbuminuria and arterial stiffness in hypertensive and diabetic patients.
- Author:
Lu-yan WANG
1
;
Ning-ling SUN
;
Ling CHANG
;
Xi-rong LIU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Albumins; analysis; Albuminuria; Arteries; physiopathology; Creatinine; urine; Diabetes Mellitus; physiopathology; urine; Elasticity; Female; Humans; Hypertension; physiopathology; urine; Male; Middle Aged
- From: Chinese Journal of Cardiology 2006;34(5):387-390
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the relationship between microalbuminuria and arterial compliance in hypertensive and diabetes patients.
METHODSA total of 200 patients with essential hypertension and/or diabetes were studied. Albumin/creatinine ratio (ACR) was determined. Carotid to femoral Pulse Wave Velocity (PWV), C(1) and C(2) were measured by a Complier Colson device and DO-2020, respectively.
RESULT(1) C(1) and C(2) were lower and PWV higher in high ACR group than in normal ACR group (P < 0.01). (2) In patients younger than 60 years, C(1) was lower and PWV higher in high ACR group than that in normal ACR group (P < 0.01). In patients older than 60 years, C(1), C(2) were lower in high ACR group than in normal ACR group.
CONCLUSIONThe results indicated that compliance of large and small vessels in hypertensive and diabetic patients decreased with increasing ACR.
