The relationship between high sensitivity C-reactive protein level at admission and myocardial perfusion after primary percutaneous intervention in patients with acute myocardial infarction.
- Author:
Yu-chen ZHANG
1
;
San-qing JIA
;
Lei WANG
;
Hong-wei LI
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Angioplasty, Balloon, Coronary; C-Reactive Protein; metabolism; Female; Humans; Male; Middle Aged; Myocardial Infarction; blood; therapy; Myocardial Reperfusion
- From: Chinese Journal of Cardiology 2006;34(5):422-424
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEThis study was designed to investigate the relationship between high sensitivity C-reactive protein (hs-CRP) level at admission and myocardial perfusion after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction.
METHODSThe study population consisted of 197 patients (154 men, mean age 60.94 +/- 11.62 years) who were admitted to our hospital with first acute myocardial infarction and underwent primary PCI in the infarct-related artery. Myocardial perfusion was evaluated by Thrombolysis In Myocardial Infarction (TIMI) myocardial perfusion grade (TMPG). Patients were divided into two groups according to TMPG after PCI. Group 1 consisted of 39 patients with TMPG 0 - 1 and group 2 consisted of 158 patients with TMPG 2 - 3. Serum hs-CRP levels at admission were measured.
RESULTShs-CRP level at admission was significantly higher in group 1 than that in group 2 (P = 0.026).
CONCLUSIONSHigher hs-CRP level at admission in patients with acute myocardial infarction is related to poorer myocardial perfusion post primary PCI.
