An analysis on the treatment outcome of acute asthma attack.
- Author:
Do Young KIM
;
Dae Jung KIM
;
Jang Yel SHIN
;
Hyo Kyoung PARK
;
Jin Suk KIM
;
Yeong Yeon YUN
;
Cheol Woo KIM
;
Jung Won PARK
;
Chein Soo HONG
- Publication Type:Original Article
- Keywords:
Acute asthma attack;
beta 2 agonist;
Aminophylline
- MeSH:
Aminophylline;
Asthma*;
Consensus;
Emergency Service, Hospital;
Emergency Treatment;
Heart Rate;
Humans;
Inhalation;
Ipratropium;
Korea;
Methylprednisolone;
Oxygen;
Potassium;
Respiratory Rate;
Treatment Outcome*
- From:Journal of Asthma, Allergy and Clinical Immunology
2000;20(1):78-84
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVE: There has been little clinical data on the treatment outcome of patients with acute asthma attack in Korea. We designed a management protocol of acute asthma, and analyzed clinical p arameters obtained from this protocol. METHOD: A total of 32 cases with acute asthma were treated with oxygen, beta2 agonist, and methylprednisolone. Ipratropium was added in cases of severe attack. After 90 minutes, intravenous aminophylline was given to the patients with poor response. RESULT: Beta2 agonist and methylprednisolone were sufficient for symptom control in 17 cases. Ipratropium and aminophylline were added in 6 and 9 cases, respectively. There was no difference in improvement of PEF, heart rate, respiratory rate, PaO2, PaCO2, and SaO2 at 90 minutes and 8 hours between beta2 agonist inhalation and subcutaneous group. Serum potassium concentration levels significantly decreased in patients treated with ipratropium of aminophylline(n=15, 4.17+/-0.45 vs. 3.99+/-0.35mM/L, p<0.05), compared with patients using only beta2 agonist and methylprednisolone(n=17, 3.89+/-0.30 vs. 4.14+/-0.45mM/L, p>0.05). CONCLUSION: Subcutaneous beta2 agonist may be an alternative to inhalant beta2 agonist for the emergency treatment of acute asthma, and we think a consensus regarding use of aminophylline in the emergency room should be made.
