Diagnostic value of double contrast-enhanced ultrasonography in preoperative staging of gastric cancer.
- Author:
Cheng-long WANG
1
;
Yong-ming YANG
;
Jian CUI
;
Hong OUYANG
;
Zhe-min WANG
;
Huai-song YE
;
Hua-juan RUAN
;
Zhi-qiang ZHENG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Contrast Media; Endosonography; methods; Female; Humans; Male; Middle Aged; Neoplasm Staging; methods; Preoperative Care; Prospective Studies; Stomach Neoplasms; diagnostic imaging; pathology; surgery; Sulfur Hexafluoride
- From: Chinese Journal of Oncology 2009;31(9):701-704
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the clinical value of double contrast-enhanced ultrasonography using oral and intravenous contrast agents in preoperative staging of gastric cancer.
METHODSSixty-two patients with biopsy-proven gastric cancer were enrolled into this study, and were examined by double contrast-enhanced gastric ultrasonography preoperatively. The results were compared with postoperative pathologic findings.
RESULTSThe accuracy of oral contrast-enhanced gastric ultrasonography and double contrast-enhanced ultrasonography in determining the T stage of gastric cancer was 72.9% (T1: 66.7%, T2: 60.0%, T3: 76.9%, T4: 71.4%) and 88.1% (T1: 66.7%, T2: 80.0%, T3: 89.7%, T4: 100%), respectively, with a statistically significant difference between the two methods (P = 0.036). The sensitivity, specificity, accuracy and Youden index of oral contrast-enhanced gastric ultrasonography and double contrast-enhanced ultrasonography in assessment of lymph node metastasis were 74.5%, 66.7%, 72.9%, and 0.41 versus 89.4%, 75.0%, 86.4%, 0.76, respectively. No significant difference in the accuracy of assessment for lymph node metastasis was observed (P > 0.05).
CONCLUSIONDouble contrast-enhanced ultrasonography is useful for preoperative staging of gastric cancer, especially for T staging.