A Case of Paronychia, Acneiform Eruption and Dry Skin Induced by Iressa(R).
- Author:
Eun Young BAE
1
;
Mi Youn KIM
;
Hyung Ok KIM
;
Young Min PARK
Author Information
1. Department of Dermatology, Kangnam St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. knderma@cmc.cuk.ac.kr
- Publication Type:Case Report
- Keywords:
Iressa(R)(ZD1839);
Paronychia;
Acneiform eruption;
Xerosis
- MeSH:
Acneiform Eruptions*;
Alopecia;
Arm;
Diarrhea;
Exanthema;
Fingers;
Foot;
Granulation Tissue;
Humans;
Nausea;
Paronychia*;
Protein-Tyrosine Kinases;
Receptor, Epidermal Growth Factor;
Skin*;
Toes;
Vomiting
- From:Korean Journal of Dermatology
2004;42(5):665-668
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Iressa(R) (ZD1839) is a new anticancer agent, acting as a selective epidermal growth factor receptor tyrosine kinase inhibitor. Iressa(R) has been generally well-tolerated in cancer patients. Predominant adverse effects are an acne-like skin rash, diarrhea, nausea, vomiting, dry skin, and mild to moderate myelosuppression. The side effect of paronychia or alopecia is rare. We report a case of paronychia with granulation tissue induced by Iressa(R). Our patient complained of an acneiform eruption on his face and xerosis on his left arm and both feet as well as paronychia of several finger and toe nails.
