Transrectal real-time tissue elastography combined with grey-scale ultrasound: valuable for the diagnosis of prostate peripheral zone lesions.
- Author:
Yan ZHANG
1
;
Jie TANG
;
Yan-Mi LI
;
Xiang FEI
;
Zhi-Yan LI
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Diagnosis, Differential; Humans; Male; Middle Aged; Predictive Value of Tests; Prostate; diagnostic imaging; Prostatic Neoplasms; diagnostic imaging; Rectum; diagnostic imaging; Sensitivity and Specificity; Ultrasonography, Interventional; methods
- From: National Journal of Andrology 2010;16(11):979-983
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the value of strain patterns by transrectal real-time tissue elastography (TRTE) combined with transrectal ultrasonography (TRUS) in the differential diagnosis of the peripheral zone lesions of the prostate.
METHODSA total of 145 patients suspected of prostate cancer (PCa) underwent TRUS and TRTE examinations. Based on the features of the strain patterns, the lesions were classified into 5 grades, and the strain patterns were compared with the results of pathological diagnosis.
RESULTSHigh-quality images of TRTE were obtained in 124 (52 malignant and 72 benign) of the cases. According to the pathological results, malignancies accounted for 6.8% (3/44) in Grade I, 23.1% (3/13) in Grade II, 31.3% (5/16) in Grade III, 75.6% (31/41) in Grade IV and 100% (10/10) in Grade V, with statistically significant differences among the 5 grades (chi2 = 57.9, P < 0.01), and the diagnostic sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV) were 88.5%, 70.8%, 78.2%, 68.7% and 89.5% for TRTE, in comparison with 78.8%, 86.1%, 83.1%, 80.4% and 84.9% for the combination of TRTE and TRUS.
CONCLUSIONThe combined use of strain patterns and TRUS is helpful to the differential diagnosis of prostate peripheral zone lesions.
