Phloroglucinol: safe and effective for the prevention of bladder spasm after TURP.
- Author:
Tie-Ding CHEN
1
;
Yin-Huai WANG
;
Luo-Yan YANG
;
Peng JIN
;
Jun-Bin YUAN
;
Sheng-Peng WU
;
Song-Chao LI
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Aged, 80 and over; Humans; Male; Middle Aged; Phloroglucinol; therapeutic use; Postoperative Complications; prevention & control; Transurethral Resection of Prostate; adverse effects; Urinary Bladder Neck Obstruction; etiology; prevention & control
- From: National Journal of Andrology 2010;16(11):1004-1006
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the efficacy of phloroglucinol in preventing bladder spasm after transurethral resection of the prostate (TURP).
METHODSUsing the random sampling method, we assigned 74 cases of TURP into a treatment group (n = 39), given 80 mg phloroglucinol every day for 3 days, and a control group (n = 35), left untreated. Then we observed the frequency, duration and pain of bladder spasm within the 3 days and compared them between the two groups.
RESULTSThe mean frequency, duration and pain visual analogue score of bladder spasm were (4.3 +/- 1.2) times, (7.2 +/- 2.1) min and 3.2 +/- 1.6 respectively in the treatment group, as compared with (7.5 +/- 2.4) times, (15.6 +/- 6.8) min and 4.7 +/- 2.3 in the control, with statistically significant differences between the two groups (P < 0.05). And no obvious adverse reactions were found in the treatment group.
CONCLUSIONPhloroglucinol is safe and effective for the prevention and treatment of bladder spasm following TURP.