A new sesqui-norlignan from Herpetospermum pedunculosum.
- Author:
Mei ZHANG
1
;
Xiao-ping DONG
;
Yun DENG
;
Hui WANG
;
Xiao-nian LI
;
Qin SONG
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography, Gel; methods; Chromatography, High Pressure Liquid; Cucurbitaceae; chemistry; Lignans; chemistry; isolation & purification; Molecular Structure; Phenols; chemistry; isolation & purification; Plants, Medicinal; chemistry; Seeds; chemistry; Silica Gel; Silicon Dioxide
- From: Acta Pharmaceutica Sinica 2006;41(7):659-661
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo study the chemical components from the bioactive extract of Herpetospermum pedunculosum, a Tibetan medicinal herb for liver diseases.
METHODSThe isolation and purification of this extract were conducted by means of silica gels column chromatography and preparative HPLC. The structures of the compounds were elucidated based on their physical and chemical features, and spectral data.
RESULTSTwo lignans were isolated from this extract. They were elucidated as herpetone (I), dehydrodiconiferyl alcohol (II).
CONCLUSIONCompound I is a new compound with the rare structure of sesqui-norlignan. Compound II is isolated from the genus of Herpetospermum for the first time.
