The digital criterion of the potential information characteristics of the traditional Chinese medicine chromatographic fingerprints.
- Author:
Guo-xiang SUN
1
;
Zhi-fei HOU
;
Yu-meng BI
;
Kai-shun BI
;
Yu-qing SUN
Author Information
- Publication Type:Journal Article
- MeSH: Asteraceae; chemistry; Chromatography, High Pressure Liquid; methods; Drugs, Chinese Herbal; chemistry; isolation & purification; Ginkgo biloba; chemistry; Medicine, Chinese Traditional; Plant Leaves; chemistry
- From: Acta Pharmaceutica Sinica 2006;41(9):857-862
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo exploit the characteristic digital criterion for the potential information characteristics of traditional Chinese medicine chromatographic fingerprints, the 37 parameters such as F and I were firstly proposed to disclose the potential information characteristics of traditional Chinese medicine fingerprints.
METHODSThe HPLC fingerprints of the Ginkgo biloba extract (GBE) , Ginkgo leaf extract and diphyridamole injection (GLEDI), Ixeris sonchifolia Hance (ISH) and Ixeris sonchifolia Hance injection (ISHI) were compared each other.
RESULTSAs far as the peak signal intensity, the uniform of peak signal, resolution and the fingerprint information were concerned. The GBE fingerprint was better than the GLEDI's, and the ISH fingerprint was also better than the ISHI's, then GBE fingerprint was close to the ISHI' s.
CONCLUSIONThe 37 parameters such as F and I can be used to objectively, authentically and thoroughly display the potential information characteristics of the traditional Chinese medicine chromatographic fingerprints.
