A new indole alkaloid glycoside from stems of Nauclea officinalis.
- Author:
Wei-dong XUAN
1
;
Hai-sheng CHEN
;
Jun BIAN
Author Information
- Publication Type:Journal Article
- MeSH: Carbolines; chemistry; isolation & purification; Glucosides; chemistry; isolation & purification; Glycosides; chemistry; isolation & purification; Indole Alkaloids; chemistry; isolation & purification; Iridoid Glucosides; Iridoids; chemistry; isolation & purification; Molecular Conformation; Molecular Structure; Plant Stems; chemistry; Plants, Medicinal; chemistry; Rubiaceae; chemistry
- From: Acta Pharmaceutica Sinica 2006;41(11):1064-1067
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo investigate the chemical constituents of water-soluble part of stem of Nauclea officinalis.
METHODSThe compounds were isolated and purified by resins, silica gel, and Sephadex LH20 column chromatography repeatedly, and their structures were identified by spectral analysis.
RESULTSSeven compounds were isolated and identified as: naucleamide A-10-O-beta-D-glucopyranoside (I), 5-beta-carboxystrictosidin (II), sweroside (III), loganin (IV), 3,4-dimethoxyphenyl-beta-D-glucopyranoside (V), 3, 4, 5-trimethoxyphenyl-beta-D-glucopyranoside (VI), 2-phenethylrutinoside (VII).
CONCLUSIONCompound I is a new indole alkaloid glucoside, compounds I-VII were isolated from this plant for the first time.
