Study on the bioavailability of amoxicilline in the form of granules for syrup
- Author:
Hoa Thi Phan
- Publication Type:Journal Article
- Keywords:
amoxicilline
- MeSH:
Amoxicillin;
Pharmaceutical Preparations
- From:Pharmaceutical Journal
2000;269(12):21-23
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The bioavailability of amoxicilline for oral suspension was studied. The plasma concentrations of amoxicilline were measured by high pressure liquid chromatography (HPLC) using UV detector. The results of this study indicate that peak concentration (Cmax) of amoxicillin for oral suspension is 35.8 mcg/ml, time of peak concentration (tmax) is 1h and relative bioavailability is 137% and 169.5% comparing with capsules of Hamburg, pharmaceutical factory B, respectively.