The risk factor for metastasis in Level IV in tongue cancer patients.
- Author:
Chuanzhen LI
1
;
Chuanbin GUO
2
;
Email: GUODAZUO@SINA.COM.
Author Information
- Publication Type:Journal Article
- MeSH: Age Factors; Carcinoma, Squamous Cell; Chi-Square Distribution; Female; Humans; Lymph Nodes; pathology; Lymphatic Metastasis; Male; Neck; Neck Dissection; Regression Analysis; Risk Factors; Sex Factors; Tongue Neoplasms; pathology
- From: Chinese Journal of Stomatology 2015;50(6):366-368
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the risk factor for metastasis in Level IV of ipsilateral neck in tongue cancer patients.
METHODSA total of 248 tongue caner paitents (255 necks) that underwent radical neck dissection was enrolled in the study. Chi-square test and Logistic regression analysis were used to determine the factors associated with metastasis in Level IV. The variable included age, sex, growth type, T stage, histopathological grade, Level III involvement, number of positive lymph nodes in Levels I-III.
RESULTSOut of 147 cases (152 necks) with positive lymph node, 21 necks (8.2%, 21/255) had Level III involvement, and 2 necks (0.8%, 2/255) developed skip metastasis. Chi-square test showed that age (P = 0.020), Level III involvement (P = 0.000), number of positive Level (≥ 2 Levels) in Levels I-III (P = 0.006), and number of positive lymph node (≥ 3 nodes) in Levels I-III (P = 0.000) were identified as independent risk factor. Logistic regression analysis revealed that only Level III involvement (P = 0.003) was the risk factor for metastasis in Level IV.
CONCLUSIONSIn tongue cancer patients, Level III involvement was a high risk factor for metastasis in Level IV.
