Research on piezoelectric protein sensor array for rapid detecting HIV(1+2) antibody.
- Author:
Ying WEN
1
;
Guiqiu SHAN
;
Jinhui PU
;
Zhongming LIU
Author Information
1. Department of Blood Transfusion, General Hospital of Guangzhou Command, Guangzhou 510010, China. yingw07@126.com
- Publication Type:Journal Article
- MeSH:
Biosensing Techniques;
instrumentation;
methods;
Electrodes;
HIV;
isolation & purification;
HIV Antibodies;
blood;
Humans;
Immunoassay;
methods;
Protein Array Analysis;
instrumentation;
methods;
Quartz;
Reproducibility of Results;
Sensitivity and Specificity
- From:
Journal of Biomedical Engineering
2009;26(4):883-885
- CountryChina
- Language:Chinese
-
Abstract:
To research piezoelectric immunosensor array for rapid detecting HIV(1+2), piezoelectric immunosensor array matrix was designed. HIV(1+2)C1 antigen was immobilized onto the silver electrodes of quartz-crystal microbalance, which was modified with adsorption and cross-linked method. In the clean air flow and monitoring environment, standard quality control and clinical serum sample were detected. The linear range for the measurement of HIV(1+2) was 0.01-0.2 NCU/ml. The sensitivity, specificity and accuracy of HIV(1+2) piezoelectric protein sensor array were 91.7%, 93.3% and 92.7% respectively.
