Radiotherapy of unicentric mediastinal Castleman's disease.
- Author:
Yue-Min LI
1
;
Peng-Hui LIU
;
Yu-Hai ZHANG
;
Huo-Sheng XIA
;
Liang-Liang LI
;
Yi-Mei QU
;
Yong WU
;
Shou-Yun HAN
;
Guo-Qing LIAO
;
Yong-Dong PU
Author Information
1. Cancer Center, PLA 309 Hospital, Beijing 100091, P.R. China.
- Publication Type:Case Reports
- MeSH:
Antigens, CD20;
metabolism;
Castleman Disease;
diagnosis;
immunology;
pathology;
radiotherapy;
surgery;
Female;
Follow-Up Studies;
Humans;
Mediastinal Diseases;
diagnosis;
immunology;
pathology;
radiotherapy;
surgery;
Mediastinum;
diagnostic imaging;
pathology;
Middle Aged;
Multimodal Imaging;
Positron-Emission Tomography;
Radiotherapy, Intensity-Modulated;
Tomography, X-Ray Computed
- From:Chinese Journal of Cancer
2011;30(5):351-356
- CountryChina
- Language:English
-
Abstract:
Castleman's disease is a slowly progressive and rare lymphoproliferative disorder. Here, we report a 55-year-old woman with superior mediastinal Castleman's disease being misdiagnosed for a long term. We found a 4.3 cm mass localized in the superior mediastinum accompanied with severe clinical symptoms. The patient underwent an exploratory laparotomy, but the mass failed to be totally excised. Pathologic examination revealed a mediastinal mass of Castleman's disease. After radiotherapy of 30 Gy by 15 fractions, the patient no longer presented previous symptoms. At 3 months after radiotherapy of 60 Gy by 30 fractions, Computed tomography of the chest showed significantly smaller mass, indicating partial remission. Upon a 10-month follow-up, the patient was alive and free of symptoms.
