Network systems biology for targeted cancer therapies.

Author: Ting-Ting ZHOU ¹
Author Information

1. Department of Immunology, Institute of Basic Medical Sciences, Academy of Military Medical Sciences, Beijing 100850, P. R. China. zhoutingting@bmi.ac.cn
Publication Type:Journal Article
MeSH: Antineoplastic Agents; therapeutic use; Drug Discovery; methods; Drug Resistance, Neoplasm; Humans; Models, Biological; Molecular Targeted Therapy; Neoplasms; drug therapy; Systems Biology; methods
From:Chinese Journal of Cancer 2012;31(3):134-141
CountryChina
Language:English
Abstract: The era of targeted cancer therapies has arrived. However, due to the complexity of biological systems, the current progress is far from enough. From biological network modeling to structural/dynamic network analysis, network systems biology provides unique insight into the potential mechanisms underlying the growth and progression of cancer cells. It has also introduced great changes into the research paradigm of cancer-associated drug discovery and drug resistance.