Treatment of declining in ovarian reserve by shen-reinforcing and menstrual cycle-regulating therapy combined with western medicine: a clinical observation.
- Author:
Xiao-tao HUANG
;
Shao-rong LIANG
;
Lu WANG
- Publication Type:Journal Article
- MeSH: Adult; Drugs, Chinese Herbal; therapeutic use; Estradiol; blood; Female; Follicle Stimulating Hormone; blood; Hormone Replacement Therapy; Humans; Integrative Medicine; Luteinizing Hormone; blood; Ovarian Diseases; drug therapy; Ovarian Follicle; drug effects; Ovarian Reserve; Young Adult
- From: Chinese Journal of Integrated Traditional and Western Medicine 2014;34(6):688-690
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the clinical effect of Shen-reinforcing and menstrual cycle-regulating therapy (SRMCRT) combined with Western medicine (WM) in treating decline in ovarian reserve (DOR).
METHODSTotally 78 patients with DOR were assigned to the traditional Chinese medicine combined WM group (abbreviated as IM group, 40 cases), and the WM group (38 cases) according to random digit table method. Patients in the WM group were treated with hormone replacement therapy, while those in the IM group additionally received SRMCRT. The therapeutic course for all was 3 consecutive months. The therapeutic efficacy was compared between the two groups. The serum levels of follicle stimulating hormone (FSH), FSH/luteinizing hormone (LH), and estradiol (E2), as well as the development of sinus follicles were compared between before and after treatment in the two groups.
RESULTSThe therapeutic effective rate was 92.5% in the IM group, higher than that of the WM group (73.68%, P < 0.05). The serum levels of FSH, FSH/LH, and E2 decreased (P < 0.05) and the number of the sinus follicle increased (P < 0.05) in the two groups after treatment. Besides, IM was superior in decreasing serum levels of FSH and FSH/LH, and increasing the number of the sinus follicle (P < 0.05).
CONCLUSIONSSRMCRT was an effective method for treating ROD. IM was superior in decreasing serum levels of FSH and FSH/LH, and increasing the number of the sinus follicle.