A sero-epidemiologiecal study on hepatitis B among general population in Beijing.
- Author:
Jiang WU
1
;
Wei ZHANG
;
Li-li HAN
;
Chang-ying LIN
;
Hui LIN
;
Yu-lan XING
;
Pei GAO
;
Xiao-hong GONG
;
Li-rong LIU
;
Fang HUANG
;
Jian-ying LIU
;
Li-ying LIU
;
Hua-yong WANG
;
Hai-zhu YU
;
Xiu-jun LIU
;
Ya-qing TANG
;
Yong-lan PU
;
Wei ZHAO
;
Chen WANG
;
Zhen ZHANG
;
Li-xian MA
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Age Distribution; Child; Child, Preschool; China; epidemiology; Hepatitis B; blood; epidemiology; immunology; prevention & control; Hepatitis B Antibodies; immunology; Hepatitis B Surface Antigens; immunology; Hepatitis B Vaccines; therapeutic use; Humans; Infant; Middle Aged; Young Adult
- From: Chinese Journal of Epidemiology 2007;28(6):555-557
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the serological infection rate of hepatitis B virus (HBV) in general population aged over one year old in Beijing and to provide information for control and prevention of the disease.
METHODSA multistage randomized cluster sampling was carried out in general population of Beijing, aged over one year old. Every study subject's hepatitis B immunization history and main risk factors were investigated through questionnaire. Venous blood samples were collected and then tested for five hepatitis B serological antigens and antibodies by means of Abbott Microparticle Enzyme Immunoassy method.
RESULTSThe prevalence rates of HBsAg, anti-HBs, anti-HBc and total HBV infection rate were 3.49% (95% CI:2.99-3.99), 37.79% (95% CI: 36.46-39.12), 35.04% (95% CI: 33.72-36.35) and 35.09% (33.78-36.40) respectively. The age standardized rates were 3.02% ,42.47% ,26.86% and 26.90% respectively.
CONCLUSIONAchievement in hepatitis B control and prevention was made in Beijing since the prevalence rate of hepatitis B surface antigen had been below 1% for children aged less than 5 years old. As for the general population, the prevalence rate of hepatitis B surface antigen had reduced to