Adaptive designs for clinical trial.
- Author:
Wei LI
1
;
Shan-ju HE
;
Yang WANG
;
Xiao-ru CHENG
;
Xuan JIA
Author Information
- Publication Type:Journal Article
- MeSH: Clinical Trials as Topic; methods; Humans; Research Design
- From: Chinese Journal of Epidemiology 2007;28(6):605-607
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEIn order to provide readers with general concepts and methodology on adaptive designs for clinical trial.
METHODSDefinition of adaptive designs for clinical trial and basic idea of adaptive adjustment were introduced through an example.
RESULTSThe relationship between adaptive designs and group sequential design was summarized. Ways to embody two basic statistical rules of clinical trial under adaptive adjustments setting were also introduced.
CONCLUSIONAdaptive designs provided clinical trial with a great flexibility, which could greatly improve the efficiency of clinical trial.
