Chemical constituents from twigs and leaves of Melodinus hemsleyanus.
- Author:
Jian ZHANG
1
;
Ting-Ting YANG
;
Guo-Qiang LI
;
Wen-Jing WANG
;
Xiao-Qi ZHANG
;
Wen-Cai YE
Author Information
1. Institute of Traditional Chinese Medicine and Natural Products, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, College of Pharmacy, Jinan University, Guangzhou 510632, China.
- Publication Type:Journal Article
- MeSH:
Apocynaceae;
chemistry;
Herbal Medicine;
Lignans;
analysis;
Plant Leaves;
chemistry;
Plant Stems;
chemistry;
Triterpenes
- From:
China Journal of Chinese Materia Medica
2013;38(9):1390-1393
- CountryChina
- Language:Chinese
-
Abstract:
To study the chemical constituents in the twigs and leaves of Melodinus hemsleyanus. The chemical constituents were isolated by silica gel, ODS and Sephadex LH-20 column chromatographies. Their structures were determined by chemical and spectroscopic methods. Fourteen compounds were isolated from the 95% ethanol extract of the twigs and leaves of M. hemsleyanus. Their structures were identified as 11-hydroxytabersonine (1) , venalstonid (2), sandine (3), oleanolic acid (4), ursolic acid (5), betulin (6) , (+)-pinoresinol (7), (-)-syringaresinol (8), 8-hydroxypinoresinol (9), (-)-latifolin (10) , cirsilineol (11) , loganin (12) , dibutylterephthalate (13) , and beta-sitosterol(14). Compounds 4-14 were obtained from this plant for the first time.
